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SCX HPLC Columns

Wavelength: 210nm
Temperature: 30°C
Flow Rate: 0.8mL/min

Availability: In Stock


Description of SCX HPLC columns

The SCX HPLC columns(Strong Cation Exchange) are a kind of high-efficiency ion-exchange HPLC columns. It’s a typical cation exchange column using a silica gel matrix with an aromatic sulfonic acid group as the bonding phase. It is commonly used for the separation of basic, water-soluble compounds. Specific applications include organic bases such as basic amino acids, anilines, pharmaceutically acceptable salts, inorganic cations, and nucleotides.

The bonded stationary phase is a strong cation exchange packing prepared by using high-purity silica gel with good mechanical stability as a matrix and using high-purity bonding reagents, with a mixed chemical structure of sulfonic acid groups and phenyl functional groups. Adopts a unique and innovative design, which can maximize the coverage of single-layer functional groups. Because its surface coverage has been maximized, so it has excellent stability.

Organic modifiers can be used on SCX columns to control sample retention time by changing pH, ionic strength, and organic modifier content to provide high efficiency and fast analysis

Technical Parameters of SCX Columns

  • Particle size: 5μm
  • Aperture: 120Å
  • Specific surface area: 320m²/g
  • Carbon loading: /
  • pH range: 2-8
  • Whether to seal: No

Applications of SCX HPLC Columns

  • Adopt highly controllable polymerization monolayer formation and tail sealing technology
  • Mixed chemical structure containing sulfonic acid group and phenyl functional group
  • It has dual functions of ion exchange and hydrophobic effect, so it has high selectivity and suitable retention for many compounds
  • Due to the use of polymer chemical bonding and end-sealing technology, it has excellent stability
  • Suitable for separation of cations, nitrogen, and neutral compounds


  1. Use guard column and pre-column to extend the service life of chromatographic column;
  2. After using for a period of time (about one week), it is necessary to backwash the column with pure methanol (or acetonitrile) at 1.0ml/min for 90min. Pay attention to the transition during the washing process to prevent the precipitation of buffer salts.

Technical Data

Bonded PhaseUSP NoParticle size (μm)Pore sizeSurface Area (m²/g)Carbon
pH RangeEnd-capped
SCX       /5μm120320N/A2.0-8.0No

Ordering Information

Item NoDescriptionPackage (pcs/pk)
SLHSCX321150HPLC Column, SCX, 3μm, 120Å, 2.1x150mm1
SLHSCX330250HPLC Column, SCX, 3μm, 120Å, 3.0x250mm1
SLHSCX340250HPLC Column, SCX, 3μm, 120Å, 4.0x250mm1
SLHSCX34650HPLC Column, SCX, 3μm, 120Å, 4.6x50mm1
SLHSCX346100HPLC Column, SCX, 3μm, 120Å, 4.6x100mm1
SLHSCX346150HPLC Column, SCX, 3μm, 120Å, 4.6x150mm1
SLHSCX346200HPLC Column, SCX, 3μm, 120Å, 4.6x200mm1
SLHSCX346250HPLC Column, SCX, 3μm, 120Å, 4.6x250mm1
SLHSCX530250HPLC Column, SCX, 5μm, 120Å, 3.0x250mm1
SLHSCX540250HPLC Column, SCX, 5μm, 120Å, 4.0x250mm1
SLHSCX54650HPLC Column, SCX, 5μm, 120Å, 4.6x50mm1
SLHSCX546100HPLC Column, SCX, 5μm, 120Å, 4.6x100mm1
SLHSCX546150HPLC Column, SCX, 5μm, 120Å, 4.6x150mm1
SLHSCX546200HPLC Column, SCX, 5μm, 120Å, 4.6x200mm1
SLHSCX546250HPLC Column, SCX, 5μm, 120Å, 4.6x250mm1
SLHSCX560250HPLC Column, SCX, 5μm, 120Å, 6.0x250mm1
SLHSCX546250-3HPLC Column, SCX, 5μm, 300Å, 4.6x250mm1
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