Wavelength: 210 nm
Temperature: 30°C
Flow Rate: 0.8mL/min

Availability: In Stock


Description of SCX Column

The (Strong Cation Exchange)SCX column is a kind of high-efficiency ion-exchange HPLC column. It’s a typical cation exchange column using a silica gel matrix with an aromatic sulfonic acid group as the bonding phase. It is commonly used for the separation of basic, water-soluble compounds. Specific applications include organic bases such as basic amino acids, anilines, pharmaceutically acceptable salts, inorganic cations, and nucleotides.

The bonded stationary phase is a strong cation exchange packing prepared by using high-purity silica gel with good mechanical stability as a matrix and using high-purity bonding reagents, with a mixed chemical structure of sulfonic acid groups and phenyl functional groups. Adopts a unique and innovative design, which can maximize the coverage of single-layer functional groups. Because its surface coverage has been maximized, it has excellent stability.

Organic modifiers can be used on SCX columns to control sample retention time by changing pH, ionic strength, and organic modifier content to provide high efficiency and fast analysis

Technical Parameters of SCX Column

  • Particle size: 5μm
  • Aperture: 120Å
  • Specific surface area: 320m²/g
  • Carbon loading: /
  • pH range: 2-8
  • Whether to seal: No


  • Adopt highly controllable polymerization monolayer formation and tail sealing technology
  • Mixed chemical structure containing sulfonic acid group and phenyl functional group
  • It has dual functions of ion exchange and hydrophobic effect, so it has high selectivity and suitable retention for many compounds
  • Due to the use of polymer chemical bonding and end-sealing technology, it has excellent stability
  • Suitable for the separation of cations, nitrogen, and neutral compounds


  1. Use guard column and pre-column to extend the service life of the chromatographic column;
  2. After using it for a period of time (about one week), it is necessary to backwash the column with pure methanol (or acetonitrile) at 1.0mL/min for 90 mins. Pay attention to the transition during the washing process to prevent the precipitation of buffer salts.

Technical Data

Bonded PhaseUSP NoParticle size (μm)Pore sizeSurface Area (m²/g)Carbon
pH RangeEnd-capped
SCX       /5μm120320N/A2.0-8.0No

Ordering Information

Item NoDescriptionPackage (pcs/pk)
SLHSCX321150SCX, 3μm, 120Å, 2.1x150mm1
SLHSCX330250SCX, 3μm, 120Å, 3.0x250mm1
SLHSCX340250SCX, 3μm, 120Å, 4.0x250mm1
SLHSCX34650SCX, 3μm, 120Å, 4.6x50mm1
SLHSCX346100SCX, 3μm, 120Å, 4.6x100mm1
SLHSCX346150SCX, 3μm, 120Å, 4.6x150mm1
SLHSCX346200SCX, 3μm, 120Å, 4.6x200mm1
SLHSCX346250SCX, 3μm, 120Å, 4.6x250mm1
SLHSCX530250SCX, 5μm, 120Å, 3.0x250mm1
SLHSCX540250SCX, 5μm, 120Å, 4.0x250mm1
SLHSCX54650SCX, 5μm, 120Å, 4.6x50mm1
SLHSCX546100SCX, 5μm, 120Å, 4.6x100mm1
SLHSCX546150SCX, 5μm, 120Å, 4.6x150mm1
SLHSCX546200SCX, 5μm, 120Å, 4.6x200mm1
SLHSCX546250SCX, 5μm, 120Å, 4.6x250mm1
SLHSCX560250SCX, 5μm, 120Å, 6.0x250mm1
SLHSCX546250-3SCX, 5μm, 300Å, 4.6x250mm1
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