Column: XChromaTM HPLC Column, NH2, PFP, 5μm, 4.6×250mm
Wavelength: 246nm
Temp: 40°C
Flow Rate: 1.1mI/min
Injection Volume: 20μL

Availability: In Stock


Description of PFP HPLC Column

A PFP(pentafluorophenyl) HPLC column was obtained by substituting a fluorine atom for five hydrogen atoms on a phenyl column. In addition to high selectivity to fluorine-containing and halogen-containing compounds, the fluorine-containing stationary phase can also be used as a general reversed-phase stationary phase for the separation of halogen-free or chlorine-free halogen compounds to provide a CH alkyl group. The selectivity of the stationary phase is different. Widely used in RP column HPLC like biopharmaceuticals, hot products, and environmental analysis.

The fluorinated stationary phase, H on the benzene ring is substituted by F and has stronger ion exchange and polarity separation characteristics than in the alkyl stationary phase. Separation can be achieved: separation of phenols, aromatics and amines, steroids, and natural products of paclitaxel.


  1. Separation of natural products for fluorochemicals and paclitaxel
  2. PFP also has high selectivity for aromatic compounds.
  3. Can retain basic compounds, lower than the hydrophobicity of C18
  4. Can be in reverse phase, HILIC
  5. Can operate in 100% pure water mode
  6. Stable, low loss, suitable for LC-MS, LC-UV

Characteristics of PFP HPLC Column

  • Good separation selectivity for halogen-containing substances and structural isomers;
  • Providing a different selectivity than the alkane stationary phase;
  • Very strong geometric size and stereoscopic shape selectivity;
  • A compound capable of separating a positional isomer structure or an alkyl stationary phase that is difficult to separate.


  • Bonded phase: PFP (USP L11/L43)
  • Particle size: 3μm, 5μm
  • Aperture: 120Å
  • Specific surface area: 320m2/g (120Å)
  • Carbon loading: C: 13% (120Å), F: 7% (120Å)
  • Sealing: Double tailing
  • pH stability: 1.5-10.0

Ordering Information

Item NoDescriptionPackage (pcs/pk)
SLHPFP321303μm, 120Å, 2.1x30mm1
SLHPFP321333μm, 120Å, 2.1x33mm1
SLHPFP321503μm, 120Å, 2.1x50mm1
SLHPFP321753μm, 120Å, 2.1x75mm1
SLHPFP3211003μm, 120Å, 2.1x100mm1
SLHPFP3211253μm, 120Å, 2.1x125mm1
SLHPFP3211503μm, 120Å, 2.1x150mm1
SLHPFP3212003μm, 120Å, 2.1x200mm1
SLHPFP3212503μm, 120Å, 2.1x250mm1
SLHPFP330303μm, 120Å, 3.0x30mm1
SLHPFP330503μm, 120Å, 3.0x50mm1
SLHPFP330753μm, 120Å, 3.0x75mm1
SLHPFP3301003μm, 120Å, 3.0x100mm1
SLHPFP3301253μm, 120Å, 3.0x125mm1
SLHPFP3301503μm, 120Å, 3.0x150mm1
SLHPFP3302003μm, 120Å, 3.0x200mm1
SLHPFP3302503μm, 120Å, 3.0x250mm1
SLHPFP340303μm, 120Å, 4.0x30mm1
SLHPFP340503μm, 120Å, 4.0x50mm1
SLHPFP340753μm, 120Å, 4.0x75mm1
SLHPFP3401003μm, 120Å, 4.0x100mm1
SLHPFP3401253μm, 120Å, 4.0x125mm1
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