C18 Alkaline HPLC Columns

Flow Rate: 1.0 mL/min
Detector: 225nm
Temperature: 30°C
Injection Volume: 20μL


Description of C18 Alkaline HPLC Columns

The C18 Alkaline HPLC columns are a new generation of different selective C18 developed by Hawach. It has hydrophobic interaction and electrostatic interaction. It has a hydrophilic group embedded in it to make it hydrophilic. The hydrophilic group replaces a large amount of silicon.

This HPLC column is widely used for basic compounds. The alcohol-based site can effectively prevent the interaction between the alkaloid and the silanol group, and the alkaline substance has a good peak shape.

Characteristics of C18 Alkaline HPLC Columns

Octadecylsilyl silica gel HPLC column
Relatively weaker polarity than C8 HPLC column
The peak shape of the alkaline substance is better, and the material having a poor peak shape on the conventional double-sealed C18 has a better peak shape;
The rapid separation of similar samples by the mobile phase is hydrophilic, and the mobile phase of the high water ratio can be used, which is extremely stable.


Bonded phase: C18 (USP L1)
Particle size: 3μm, 5μm
Aperture: 120Å
Specific surface area: 320m²/g (120Å)
Carbon loading: 12% (120Å)
Sealing: Double tailing
pH stability: 1.5-10.0

Technical Data

Bonded PhaseUSP NoParticle size (μm)Pore sizeSurface Area (m²/g)Carbon
pH RangeEnd-capped
C18-Alkaline L13um, 5um 10um 120Å 32012%1.5-10No

Ordering Information

Item NoDescriptionPackage (pcs/pk)
SLHC18AL546150HPLC Column, C18-Alkaline, 5μm, 120Å, 4.6x150mm1
SLHC18AL546250HPLC Column, C18-Alkaline, 5μm, 120Å, 4.6x250mm1
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